Principal Data Scientist

Salary: CHF 100'000 - 130'000 per year

Requirements:

• A PhD in Epidemiology, Biostatistics, Data Science, Bioinformatics, or a related field
• 3+ years of experience applying real-world data analysis in pharmaceutical research

Responsibilities:

• Lead the design and execution of complex real-world data analyses to guide investment and clinical decisions across early-phase programmes
• Ensure our real-world data outputs are reproducible, statistically rigorous, and built using scalable, reusable analytical frameworks
• Use real-world data to optimise Phase I/II settings through cohort definition, endpoint exploration, and the development of external control arms
• Combine real-world data with biomarker and omics data to map patient trajectories and enable targeted, personalised treatment approaches
• Act as a technical and scientific lead to develop junior talent and foster a high-performing, collaborative research culture
• Serve as a trusted scientific liaison between data functions and clinical stakeholders to align evidence generation with portfolio priorities

Technologies:

• Support

More:

We are part of the Computational Medicine organization within the Computational Biology and Medicine department, where we deliver world-leading real-world data analytical capabilities at scale. We work with other real-world data experts and collaboration partners to design and execute high-impact studies that improve our understanding of disease biology, inform biomarker strategies, and generate actionable insights into patient populations and treatment outcome prediction. We integrate diverse real-world data sources such as EHR, claims, registries, and linked datasets, and we apply advanced analytical approaches to support clinical development decisions. We also contribute to the broader scientific and technical strategy, establish methodological standards and scalable analytical solutions, and mentor and develop talent while driving best practices in real-world data analysis.

last updated 27 week of 2026