Senior ADS Programmer

Salary: CHF 100'000 - 130'000 per year

Requirements:

• You hold a Bachelors or Masters degree in Statistics, Computer Science, Mathematics, Life Sciences, or a related field
• You have a minimum of 5 years of experience in statistical programming in a clinical development setting, or an advanced degree with 3 years of equivalent work experience
• You are proficient in or have working knowledge of a modern programming language (such as SAS or R) and visualization/review tools
• You have a deep understanding of statistical quality, endpoints, and QC processes
• You have experience with CDISC standards (e.g., SDTM and ADaM)
• You bring expertise in handling and analyzing different types of data (multi-modal)
• You have demonstrated ability to deliver programming outputs independently
• You demonstrate respect for cultural differences when interacting with colleagues in the global workplace
• You are fluent in English
• Possess attention to detail for regulatory submission processes and related documentation
• Demonstrate critical thinking, strong organizational and problem-solving skills
• Experience working in cross-functional global study teams
• Effective communication skills with the ability to translate complex statistical concepts for non-statistical audiences
• Experience with multiple phases of drug development (early and/or late stage)
• Excellent communication skills, including the ability to influence and translate complex data for non-technical stakeholders
• Demonstrated willingness to adapt, grow, and evolve in response to shifting priorities

Responsibilities:

• We independently develop, validate, and maintain datasets and statistical outputs for clinical trials, including SDTM datasets, ADaM datasets, and tables, listings, and figures (TLFs), ensuring programming accuracy, traceability, and compliance with internal processes and regulatory expectations
• We develop and support programming outputs across a wide range of data types, including exploratory biomarker data and real-world data, to support both regulatory and scientific objectives
• We collaborate on exploratory analyses that span disease areas and therapeutic areas, enabling insight generation to inform drug development strategies
• We support the creation and refinement of interactive tools and analytical applications (e.g., dashboards or visual data platforms) that enable dynamic exploration of integrated datasets by scientific and clinical teams
• We provide programming leadership for assigned studies, coordinating deliverables across internal and external programming partners to meet study timelines and requirements
• We interpret statistical analysis plans and translate them into executable programming specifications to ensure scientific rigor in outputs
• We troubleshoot and resolve technical programming challenges with limited supervision, proactively identifying risks and implementing effective solutions while meeting timelines
• We contribute to the design and maintenance of standard macros and reusable components, promoting efficiency and consistency across multiple studies and projects
• We document programming workflows and maintain audit trails, ensuring study files are complete, traceable, and inspection-ready
• We work cross-functionally with stakeholders, including biostatistics, data management, and clinical operations, to define programming timelines and deliverables
• We engage in process improvement and innovation activities and participate in learning activities to grow knowledge of clinical research and programming standards

Technologies:

• Support
• SAS

More:

We are Roche, and this role sits within Analytical Data Science, a core function in Product Development Data Sciences (PDD), where we provide strategic leadership and scientific rigor across development. Our PDD Analytical Data Science teams work across the portfolio to generate data-driven insights, identify opportunities for scale, and deliver impactful solutions as an agile workforce supporting regulatory commitments. We are recognized as a leading hub for top industry talent and focus on digital and automation solutions, analytical approaches for exploratory analyses, and consistent statistical programming practices across early- and late-stage clinical development. This position is based in Basel. Relocation assistance is not available.

last updated 27 week of 2026